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Italy-AL-AL Azienda Directories
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Azienda News:
- WNT and NOTCH signaling in human trophoblast development and . . .
Herein, we discuss Wingless (WNT) and NOTCH signaling, two pathways that play pivotal roles in human placenta and trophoblast development Whereas WNT is necessary for expansion of trophoblast progenitors and stem cells, NOTCH1 is required for proliferation and survival of EVT precursors
- NOTUM-mediated WNT silencing drives extravillous . . . - PNAS
We demonstrate that canonical activation of WNT signaling can block EVT cell differentiation and identify a critical role for NOTUM in facilitating EVT cell differentiation through attenuating canonical WNT signaling
- Wnt Signalling in Implantation, Decidualisation and Placental . . .
In mice, Wnt signalling promotes early trophoblast lineage development, blastocyst activation, implantation and chorion–allantois fusion Moreover, different Wnt ligands play essential roles in the development of the murine uterine tract, in cycling endometrial cells and during decidualisation
- Wnt signaling in development and tissue homeostasis
The Wnt-β-catenin signaling pathway is an evolutionarily conserved cell-cell communication system that is important for stem cell renewal, cell proliferation and cell differentiation both during embryogenesis and during adult tissue homeostasis
- The role of WNT and NOTCH signaling in human trophoblast . . .
Canonical WNT signaling controls CTB progenitor expansion and regulates the migration and differentiation of EVTs, whereas NOTCH1 signaling controls EVT progenitor development and promotes their
- Human placental trophoblast invasion and differentiation: a . . .
The pathway could play a role in blastocyst adhesion, implantation and early trophoblast lineage decisions Moreover, Wnt signaling could regulate trophoblast cell fusion as well as development of the anchoring villus controlling proliferation, invasion and differentiation
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