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- Drug-Induced Esophagitis - StatPearls - NCBI Bookshelf
Low PH medicines such as doxycycline, ferrous sulfate, and ascorbic acid cause drug-induced esophagitis with a similar mechanism Reports also exist of hyperosmolar property-related local tissue destruction and vascular injury of the esophagus as a cause of potassium chloride-induced esophagitis [10]
- Doxycycline-induced pill esophagitis - PubMed
Pill-induced esophagitis is a complication seen in patients who use certain medications such as tetracycline and non-steroidal anti-inflammatory drugs In this short report, we described five cases of doxycycline-induced esophagitis with endoscopic images
- UpToDate
This webpage provides information on pill esophagitis, including causes, symptoms, diagnosis, and treatment options
- Doxycycline-Induced Pill Esophagitis: A Case Report
Pill-induced esophagitis is a recognized condition that is possibly under diagnosed Its pathogenesis is associated with the prolonged contact of the medication with the esophageal mucosa, owing to delayed esophageal transit and causing damage to the mucosa [2]
- Doxycycline-Associated Ulcerative Esophagitis: A Report of a Rare Case
Esophageal injuries are significantly more prevalent with capsule forms than tablet forms, as capsules can readily adhere to the esophageal mucosa [4] Clinical manifestations include intense retrosternal pain and dysphagia, typically manifesting hours or days after drug ingestion [3]
- What is Pill Esophagitis? - Poison Control
Tetracycline antibiotics (including doxycycline), large-sized pills, and gelatin capsules are common causes of pill esophagitis Doxycycline, iron supplements, and vitamin C pills create acidic solutions when dissolved in water or saliva
- Doxycycline-induced pill esophagitis - Thieme
Doxycycline is a common yet under-re-ported cause of pill esophagitis Mucosal injury is the result of prolonged contact of the acidic drug with the esophageal mucosa Therefore, patients who ingest the pill with insufficient water and then remain recumbent have the highest risk [1]
- Esophagitis and Doxycycline: Risks Care Tips
When taking doxycycline, it is important to be aware of how this medication can trigger or worsen esophageal inflammation, potentially leading to esophagitis As a type of medication known as a tetracycline antibiotic, doxycycline is used to treat a range of infections caused by bacteria
- Pill esophagitis - UpToDate
This topic will review medication-induced esophagitis from direct esophageal mucosal injury, also known as pill esophagitis The pathophysiology of reflux esophagitis and the clinical manifestations, diagnosis, and management of other causes of esophagitis are discussed in detail separately
- Drug-Induced Esophagitis: What Pharmacists Need to Know
Doxycycline, tetracycline, and clindamycin are the antibiotics that are most commonly associated with drug-induced esophagitis These medications have a low pH when dissolved in solution, such as saliva, and cause transient esophageal injury that heals after withdrawal
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