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USA-AZ-PRESCOTT Azienda Directories
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Azienda News:
- Animal Models of Human Disease - PMC - PubMed Central (PMC)
The use of animal models of human disease is critical for furthering our understanding of disease mechanisms, for the discovery of novel targets for treatment, and for translational research
- The Use of Animal Models in Studying Genetic Disease . . . - Nature
Animal models have greatly improved our understanding of the cause and progression of human genetic diseases and have proven to be a useful tool for discovering targets for therapeutic drugs
- Animal Models for Complex Traits and Diseases
The use of animals as models for human disease is one of the most important paradigms of biomedical research Animal models are essential tools for studing gene-gene interactions, gene-environment effects, and for preclinical testing of therapeutics
- The Promise and Perils of Animal Models - Advancing Disease . . .
Robert Burgess, principal investigator of the Jackson Center for Precision Genetics, started his presentation by asking, “What are we modeling precisely?” There are three different ways in which an animal can model a human phenotype or disease: face validity, construct validity, and predictive validity
- Animal models of human disease: Challenges in enabling . . .
Animal models have historically played a critical role in the exploration and characterization of disease pathophysiology, target identification, and in the in vivo evaluation of novel therapeutic agents and treatments
- Animal Models for Human Diseases - SpringerLink
Animal models can be grouped into one of the following five categories: (1) induced (experimental) models, (2) spontaneous (genetic, mutant) models, (3) genetically modified models, (4) negative models, and (5) orphan models
- Role of animal models in biomedical research: a review - PMC
Animal models have many facets that mimic various disease conditions in humans like systemic autoimmune diseases, rheumatoid arthritis, epilepsy, Alzheimer’s disease, cardiovascular diseases, Atherosclerosis, diabetes, etc , and many more
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