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- CHEK2 - Wikipedia
CHEK2 (Checkpoint kinase 2) is a tumor suppressor gene that encodes the protein CHK2, a serine-threonine kinase CHK2 is involved in DNA repair, cell cycle arrest or apoptosis in response to DNA damage Mutations to the CHEK2 gene have been linked to a wide range of cancers [5]
- About Mutations in the CHEK2 Gene - Memorial Sloan Kettering Cancer Center
A CHEK2 gene mutation increases your risk for certain types of cancers Your cancer risk may be different depending on the specific CHEK2 mutation you have Most CHEK2 mutations increase your risk for breast cancer
- What is CHEK2? - Dana-Farber Cancer Institute
CHEK2 is a tumor-suppressor gene that protects cells from becoming cancerous People who inherit mutations in the gene are at increased for certain types of cancer and may benefit from more frequent screening CHEK2 is the abbreviated name of the gene called checkpoint kinase 2
- CHEK2 Gene Mutations: Risks, Management and Treatment
An inherited CHEK2 mutation may affect your options for cancer prevention, detection and treatment FORCE is here to guide you
- Gene test interpretation: CHEK2 - UpToDate
This monograph summarizes the interpretation of germline testing of the CHEK2 gene It does not discuss indications for testing and is not intended to replace clinical judgment in the decision to test or in the clinical care of the individual who was tested These subjects are discussed separately OVERVIEW
- What is CHEK2? Experts discuss gene linked with breast and . . . - TODAY
CHEK2 serves the body as a tumor suppressor, but when it's mutated, it can be linked to numerous cancers It is considered a more moderate-risk gene mutation Today, most people have likely heard
- CHEK2 | Genetics and Hereditary Cancers - UT Southwestern Medical Center
What You Should Know About CHEK2 Pathogenic Likely Pathogenic Variants Individuals with a pathogenic likely pathogenic (P LP) variant in the CHEK2 gene have an increased risk for cancers of the breast and prostate
- CHEK2 Gene - GeneCards | CHK2 Protein | CHK2 Antibody
In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor
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