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Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans [5] It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes [6] and ependymal cells during development [7]
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- Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for . . .
Glial fibrillary acidic protein (GFAP) is an intermediate filament structural protein involved in cytoskeleton assembly and integrity, expressed in high abundance in activated glial cells GFAP is neuroprotective, as knockout mice are hypersensitive to traumatic brain injury
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Glial fibrillary acidic protein (GFAP) levels reflect the clinical severity and extent of intracranial pathology after traumatic brain injury (TBI) In 2018, the FDA authorized the
- Entry - *137780 - GLIAL FIBRILLARY ACIDIC PROTEIN; GFAP - OMIM
GFAP is an intermediate filament (IF) protein that is highly specific for cells of astroglial lineage (Reeves et al , 1989) Astrocytes express at least 10 different isoforms of GFAP (reviewed by Hol and Pekny, 2015) Reeves et al (1989) isolated a cDNA encoding GFAP
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