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- Ionomycin - Wikipedia
Ionomycin is an ionophore and an antibiotic that binds calcium ions (Ca 2+) in a ratio 1:1 It is produced by the bacterium Streptomyces conglobatus [3] It binds also other divalent cations like magnesium and cadmium, but binds Ca 2+ preferably [1][2] It has 14 chiral centers
- Ionomycin - an overview | ScienceDirect Topics
Ionomycin is a polyether ionophore that chelates calcium (and cadmium) in the form of dibasic acids (35) From: Archives of Medical Research, 2001
- Ionomycin | NFAT Activator - InvivoGen
Ionomycin is a membrane permeable calcium ionophore produced by the bacterium Streptomyces conglobatus This ionophore facilitates the transfer of calcium ions (Ca2+) into and out of cells Ionomycin can be used to increase intracellular calcium levels triggering cell death through apoptosis and aut
- Ionomycin (SQ23377) | Calcium Ionophore - MedChemExpress
Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba) Ionomycin (SQ23377) promotes apoptosis
- Ionomycin, Calcium Salt | Cell Signaling Technology
Ionomycin is a potent and selective calcium ionophore agent (1,2) The molecule acts as a motile Ca 2+ carrier and enhances Ca 2+ influx by direct stimulation of store-regulated cation entry across biological membranes (3) At the micromolar level, ionomycin can activate Ca 2+ Calmodulin dependent kinase and phosphatase to stimulate gene
- PMA Ionomycin in T-Cell Activation and Calcium Signaling Pathways
The ability of ionomycin to precisely modulate calcium levels makes it a powerful agent for investigating calcium-dependent signaling pathways The combined use of PMA and ionomycin creates a synergistic effect, amplifying the activation of T-cells
- Ionomycin enhances Ca2+ influx by stimulating store-regulated cation . . .
These data suggest that ionomycin acts primarily at the level of the internal Ca2+ stores, so that, at the concentrations used here (< or = 1 microM), it increases Ca2+ (and Mn2+) influx via activation of endogenous entry pathways and not by plasmalemmal translocation
- Ionomycin | C41H72O9 | CID 6912226 - PubChem
Ionomycin | C41H72O9 | CID 6912226 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety hazards toxicity information, supplier lists, and more
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