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  • Human-GEM README. md at main · SysBioChalmers Human-GEM - GitHub
    The generic genome-scale metabolic model of Homo sapiens - Human-GEM README md at main · SysBioChalmers Human-GEM
  • What next for He Jiankui, the human gene editor locked in limbo?
    The biophysicist dubbed ‘China’s Frankenstein’ vows to continue controversial research that made him a ‘public enemy’
  • Plant Com|我校在南瓜完整基因组组装和着丝粒结构研究中取得新进展-华中农业大学园艺林学学院
    近日,华中农业大学果蔬园艺作物种质创新与利用全国重点实验室、园艺林学学院孔秋生教授和别之龙教授团队在Plant Communications在线发表了题为“Complete genome assembly provides insights into centromere architecture of pumpkin (Cucurbita maxima)”的通讯论文。该研究利用HiFi、ONT三代测序数据及Hi-C技术,成功组装了第
  • 柯荣秦教授团队在《科学通报》发表原位测序进展综述文章-华侨大学医学院
    近日,我院柯荣秦教授团队在《科学通报》(中文版)上发表了题为“基于滚环扩增的原位测序空间转录组学技术研究进展”的综述文章。该文章聚焦于各类基于滚环扩增的原位测序技术,系统总结了不同技术的独特优势和特征,并阐述了这些技术在生物医学研究中的广泛应用前景。
  • ASB7 is a negative regulator of H3K9me3 homeostasis | Science - AAAS
    Next, we examined the intracellular distribution of ASB7 Cell fractionation revealed that ASB7 was enriched in chromatin and co-localized with H3K9me3 (Fig 2, A and B), indicating that ASB7 is a heterochromatin-associated protein To investigate how ASB7 is recruited to heterochromatin, we employed a TurboID-based proximity labeling assay to biotinylate ASB7-interacting proteins (), followed
  • Variational quantum eigensolver - Wikipedia
    In quantum computing, the variational quantum eigensolver (VQE) is a quantum algorithm for quantum chemistry, quantum simulations and optimization problems It is a hybrid algorithm that uses both classical computers and quantum computers to find the ground state of a given physical system Given a guess or ansatz, the quantum processor calculates the expectation value of the system with
  • Structural ubiquitin contributes to K48 linkage specificity of the HECT . . .
    The HECT ubiquitin ligase family is characterized by a conserved ∼350 aa HECT domain that folds into a bi-lobal catalytic module located at the C terminus 7, 8 During catalysis, ubiquitin forms a labile thioester intermediate with the HECT domain catalytic cysteine, forming an E3-ubiquitin intermediate The ubiquitin molecule is then transferred from the HECT catalytic cysteine directly to
  • Fast Whole-Genome Sequencing to Identify Outbreaks
    A, Phylogenetic tree based on whole-genome sequencing analysis The whole genome sequence of E cloacae ATCC 13047 was used as the mapping reference Putative outbreak isolate genomes are shown in red, controls in blue, and the reference isolate in black




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