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- HER2 - Wikipedia
HER2 is named as such due to structural similarities with human epidermal growth factor receptor 1, or HER1 The Neu alias of HER2 derives its name from the parent glioblastoma cell line - a type of neural tumor found in rodents
- HER2-positive breast cancer: What is it? - Mayo Clinic
HER2-positive breast cancer is a breast cancer that tests positive for a protein called human epidermal growth factor receptor 2 (HER2) This protein promotes the growth of cancer cells In about 1 of every 5 breast cancers, the cancer cells have extra copies of the gene that makes the HER2 protein
- HER2 positive breast cancer: What it is, diagnosis and . . .
The human epidermal growth factor 2 – also known as HER2 – is a protein that tells human cells when to grow and when not to grow Sometimes, a random genetic mutation or extra copies of the gene that encodes HER2 make these cells grow even when they shouldn’t
- A Comprehensive Review of HER2 in Cancer Biology and . . .
Dysregulation of HER2 The expression of HER2 is primarily regulated at the level of gene transcription Transcription factors and epigenetic modifications can regulate HER2 gene expression by modulating the chromatin structure and accessibility to transcriptional machinery
- HER 2: Biology, Detection, and Clinical Implications - PMC
Abstract Context HER2 is a membrane tyrosine kinase and oncogene that is overexpressed and gene amplified in about 20% of breast cancers When activated it provides the cell with potent proliferative and anti-apoptosis signals and it is the major driver of tumor development and progression for this subset of breast cancer
- Cancer du sein HER2 : positif, négatif, traitement, cest quoi
Le cancer du sein HER2+ ou "HER2 positif" représente 15 à 20% de tous les cancers du sein La découverte des thérapies ciblées a permis d'améliorer son pronostic et la qualité de vie des patientes
- All About HER2 Status in Breast Cancer | Breast Cancer . . .
About 15 to 20 percent of breast cancer patients have HER2-positive breast cancer It is an invasive form of the disease that grows rapidly and is more likely to spread beyond the breast compared to other breast cancer subtypes
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