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- Transthyretin - Wikipedia
Transthyretin (TTR or TBPA) is a transport protein in the plasma and cerebrospinal fluid that transports the thyroid hormone thyroxine (T 4) and retinol to the liver This is how transthyretin gained its name: trans ports thy roxine and retin ol
- Transthyretin Amyloidosis (ATTR-CM): Types, Causes, Treatment
Transthyretin amyloidosis (ATTR-CM) occurs when your liver produces faulty transthyretin (TTR) proteins Clumps of these abnormal proteins (called fibrils) build up in your heart’s main pumping chamber
- A Narrative Review of the Role of Transthyretin in Health and Disease
Transthyretin is a highly conserved protein that transports the thyroid hormone thyroxine and the retinol-binding protein bound to retinol (vitamin A) Mutations in TTR are associated with ATTR amyloidosis, a progressive, debilitating, and ultimately fatal disease
- Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Transthyretin (trans-thy-re-tin) amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed and potentially fatal disease of the heart muscle In ATTR-CM, a protein called transthyretin that normally circulates in the bloodstream becomes misshapen and builds up in the heart, nerves and other organs
- A Narrative Review of the Role of Transthyretin in Health and . . . - PubMed
Transthyretin (TTR) is a tetrameric transport protein highly conserved through vertebrate evolution and synthesized in the liver, choroid plexus, and retinal pigment epithelium TTR transports the thyroid hormone thyroxine and the retinol-binding protein (RBP) bound to retinol (vitamin A)
- Transthyretin - an overview | ScienceDirect Topics
Transthyretin is a 55,000-Dalton protein that is synthesized primarily in the liver, and serves as the primary serum transport protein for holo-retinol-binding protein and a minor transport protein for thyroxine
- Transthyretin | definition of transthyretin by . . . - Medical Dictionary
A protein component of plasma having a molecular weight of about 55,000 and containing 1 3% carbohydrate; estimated plasma concentration is 0 3 g per 100 mL; abnormal levels of prealbumin are found in cases of familial amyloidosis Synonym (s): transthyretin 2
- List of Transthyretin stabilizers + Uses, Types Side Effects - Drugs. com
Transthyretin (TTR) stabilizers prevent destabilization of TTR hometramer complex and dissociation into amyloid fibrils, therefore preventing progression of TTR amyloidosis TTR is a transport protein made up of 127 amino acids that carries both thyroxine (T4) and retinol-binding protein-bound to retinol
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