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- WNK1 - Wikipedia
WNK (lysine deficient protein kinase 1), also known as WNK1, is an enzyme that is encoded by the WNK1 gene [5] [6] [7] [8] [9] WNK1 is serine-threonine protein kinase and part of the "with no lysine K" kinase WNK family
- WNK1 Gene - GeneCards | WNK1 Protein | WNK1 Antibody
WNK1 (WNK Lysine Deficient Protein Kinase 1) is a Protein Coding gene Diseases associated with WNK1 include Pseudohypoaldosteronism, Type Iic and Neuropathy, Hereditary Sensory And Autonomic, Type Iia Among its related pathways are Ion channel transport and Apoptotic Pathways in Synovial Fibroblasts
- Emerging role of WNK1 in pathologic central nervous system signaling
WNK1 (with no lysine (K)) is a widely expressed serine threonine protein kinase The role of this kinase was first described in the kidney where it dynamically controls ion channels that regulate changes in cell volume
- An update regarding the role of WNK kinases in cancer
WNK1 is found to repress autophagy in Hela and A549 cancer cell lines through complex mechanisms: Through inhibiting AMPK signaling, WNK1 inhibits the phosphorylation and activity of the
- WNK kinases sense molecular crowding and rescue cell . . . - Cell Press
WNK1 is a molecular crowding sensor that undergoes cell shrinkage-dependent phase separation to restore cell volume This study provides a clear link between the intrinsically disordered region-mediated phase separation of a protein and cell physiology
- WNK1 WNK lysine deficient protein kinase 1 [ (human)]
WNK1 Enhances Migration and Invasion in Breast Cancer Models Human adenylate kinase 6 regulates WNK1 (with no lysine kinase-1) phosphorylation states and affects ion homeostasis in NT2 cells WNK1 is an assembly factor for the human ER membrane protein complex
- WNK1, a novel mammalian serine threonine protein kinase lacking the . . .
We have cloned and characterized a novel mammalian serine threonine protein kinase WNK1 (with no lysine (K)) from a rat brain cDNA library WNK1 has 2126 amino acids and can be detected as a protein of approximately 230 kDa in various cell lines and rat tissues
- WNK1 kinase signaling in metastasis and angiogenesis
Recent studies of WNK1 have revealed that its related signaling pathways mediated tumor-induced angiogenesis and carcinogenesis and uncovered novel roles of WNK1 in endothelial cell migration and proliferation, tumor cell proliferation, and metastasis
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