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- Wnt signaling pathway - Wikipedia
In cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors The name Wnt, pronounced "wint", is a portmanteau created from the names Wingless and Int-1 [1]
- Wnt β-catenin signalling: function, biological mechanisms, and . . .
Wnt signalling plays an important role in the self-renewal of some tissues in mammals For example, the Wnt signalling pathway is related to the development and renewal of small-intestinal
- Wnt signal transduction pathways - PMC - PubMed Central (PMC)
The Wnt signaling pathway is an ancient and evolutionarily conserved pathway that regulates crucial aspects of cell fate determination, cell migration, cell polarity, neural patterning and organogenesis during embryonic development The Wnts are
- Wnt β-Catenin Signaling and Disease - Cell Press
In parallel, aberrant Wnt signaling underlies a wide range of pathologies in humans In this Review, we provide an update of the core Wnt β-catenin signaling pathway, discuss how its various components contribute to disease, and pose outstanding questions to be addressed in the future
- Wnt signaling pathway: A comprehensive review - PubMed
Wnts are extracellular secreted glycol proteins, consisted of a family of 19 human proteins that represent the complex nature of the regulatory structure and physiological efficiency of signaling
- Everything You Would Like to Know About Wnt Signaling
Wnts are secreted glycoproteins that bind to specific cell surface receptors and activate signaling in a mostly paracrine fashion Wnts trigger distinct intracellular pathways, including canonical signaling through β-catenin and noncanonical planar cell polarity (PCP) and Ca 2+ signaling (Fig 1)
- Wnt Meaning: The Wnt Signaling Pathway and Its Function
The name “Wnt” combines “Wingless,” a gene from the fruit fly Drosophila, and “Int-1,” a proto-oncogene from mice This fusion reflects the discovery that these genes were homologous, revealing a highly conserved signaling system The Wnt signaling pathway is a process initiated by these proteins that controls cell behavior
- Wnt β-catenin signaling: components, mechanisms, and diseases
We discuss Wnt ligands, agonists and antagonists and their interactions with Wnt receptors We also dissect critical events that regulate β-catenin stability from Wnt receptors to the cytoplasmic β-catenin destruction complex, and nuclear machinery that mediates β-catenin-dependent transcription
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