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Canada-0-READAPTATION Azienda Directories
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Azienda News:
- BRCA Gene Changes: Cancer Risk and Genetic Testing
A fact sheet about the BRCA1 and BRCA2 genes, what to do if a person tests positive for alterations in one of these genes, and consequences of genetic testing
- BRCA1 and BRCA2 (PDQ®) - NCI - National Cancer Institute
Evidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer This summary also contains information about the cancer risks associated with BRCA1 BRCA2, screening, risk-reduction, treatment, and prognosis
- Discovery – BRCA Connection to Breast and Ovarian Cancer
NCI-funded research helped identify inherited BRCA1 and BRCA2 genetic mutations and their connection to breast and ovarian cancer From this research, a screening test was also developed to help patients make informed decisions about their health
- Cambios en el gen BRCA: el riesgo de cáncer y las pruebas genéticas
Hoja informativa sobre los genes BRCA1 y BRCA2, qué hacer si la prueba de una persona indica que tiene cambios en uno de estos genes y las consecuencias de las pruebas genéticas
- Surgery to Reduce the Risk of Breast Cancer - NCI
Can surgery be used to reduce someone’s risk of breast cancer? Yes Risk-reducing (also called preventive or prophylactic) surgery can lower the risk of breast cancer in people who are at very high risk, such as women who carry a harmful mutation in a breast cancer susceptibility gene such as BRCA1, BRCA2, TP53, or PTEN
- MRI, Surgery Reduce Cancer Deaths in Women with BRCA Changes
For women with inherited harmful changes in BRCA genes, MRI surveillance and salpingo-oophorectomy can modestly reduce their risk of dying from breast and ovarian cancer, results from two studies show
- Cancer Risk for Women Carrying BRCA Mutations - NCI
A Cancer Currents blog post on a large, prospective study of breast, ovarian, and contralateral breast cancer risks associated with BRCA1 and BRCA2 gene mutations
- PALB2 and Associated Cancer Risks (PDQ®) - NCI
The PALB2 (Partner And Localizer of BRCA2) gene is located on chromosome 16p12 2 This gene interacts with both BRCA2 and BRCA1 to restore and maintain genomic stability via homologous recombination repair of DNA double-stranded breaks Several studies have reported a high penetrance of breast cancer in women who carry PALB2 pathogenic variants PALB2 is now included on all breast cancer
- Definition of BRCA1 gene - NCI Dictionary of Cancer Terms
A gene that makes a protein that repairs damaged DNA Mutations (changes) in the BRCA1 gene significantly increase the risk of developing breast and ovarian cancer These mutations can also increase the risk of developing other types of cancer, such as prostate cancer and pancreatic cancer The BRCA1 gene is located on chromosome 17, which is 1 of the 23 pairs of chromosomes in human cells
- Genetic Testing Fact Sheet - NCI - National Cancer Institute
A fact sheet about genetic testing for inherited cancer risk Includes who should consider testing, and how to understand test results
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